Diagnostic efficacy of conventional cytological smears and cell block of ascitic fluid for detection of malignant cell

Introduction: For identification of malignant cells in effusion, cell block is a simple, inexpensive method and no additional expatriation needed. In the its differentiation from showing reactive degenerative changes were diagnostic difficulties some cases. The yielded more cellularity provided better morphological details. Multiple sections could be obtained for special stain immunohistochemistry when required. Methods: This cross-sectional observational study was carried out at Department Pathology, Bangabandhu Sheikh Mujib Medical University (BSMMU), Dhaka, Bangladesh; March, 2017 to December, 2018. sample size 101 material ascitic fluids clinically suspected malignancy Conventional smears prepared every Both conventional slides scored according Miar’s point scoring system analyzed categories. Results: By smear, 86 cases diagnosed as negative malignancy, four suspicious remaining 11 positive malignancy. After analyzing blocks, three diagnosed, which had been by smear. Cell technique showed significant differences diagnosis effusion comparison smear (p<0.05) Conclusion: Block considered useful adjunct evaluating final cytodiagnosis, along with routine method. Mediscope 2023;10(1): 01-09